For Research Use Only. This product is supplied exclusively for laboratory research and is not intended for human or veterinary use.
5-Amino-1MQ Iodide Research Compound
5-Amino-1MQ is a small-molecule enzyme inhibitor, not a peptide. The supplied research form is identified as 5-amino-1-methylquinolinium iodide, a selective inhibitor of nicotinamide N-methyltransferase (NNMT).
Research has used it to probe NNMT-dependent nicotinamide and methyl-donor pathways in cells and rodent models. It is not an NAD+ precursor and should not be described as if it directly supplies NAD+.
Technical Specifications
| Product | 5-Amino-1MQ iodide |
|---|---|
| Full chemical name | 5-Amino-1-methylquinolinium iodide |
| Compound class | Small-molecule NNMT inhibitor |
| Chemical formula | C10H11IN2 |
| Molecular weight | 286.11 g/mol (iodide salt) |
| CAS number | 42464-96-0 |
| Purity | Above 99% by third-party HPLC testing |
| Physical form | Solid research material; colour may range from faint red to brown |
| Available format | 5mg |
| Intended use | Laboratory research and analytical use only |
Independent Batch Testing
Every current ZENTRA 5-Amino-1MQ batch is independently tested and records an HPLC purity result above 99%. Use the batch number printed on the product label to locate the corresponding third-party report in our Batch Verification and COA Centre. Researchers should consult the individual report for the exact analytical methods, result and testing date for their supplied batch.
5-Amino-1MQ Research Context
Medicinal-chemistry research identified membrane-permeable quinolinium NNMT inhibitors and evaluated 5-amino-1MQ in enzyme assays, cell systems and diet-induced-obesity mouse models.
The findings are preclinical and do not establish human safety or efficacy. Because salt form changes molecular weight and handling properties, researchers should use the iodide-salt values and consult the batch COA.
Storage and Handling
Store the unopened iodide salt at approximately -20°C, protected from light and moisture. Use a validated laboratory solvent and stability protocol appropriate to the iodide salt; bacteriostatic water is not a universal default.
5-Amino-1MQ Research FAQs
Is 5-Amino-1MQ a peptide?
No. It is a quinolinium small molecule and does not have an amino-acid sequence.
What enzyme does it inhibit?
Published research characterises it as an inhibitor of nicotinamide N-methyltransferase, or NNMT.
Is it an NAD+ precursor?
No. It is studied for indirect effects on nicotinamide and methylation pathways through NNMT inhibition.
Why does the salt form matter?
The iodide counter-ion changes the molecular formula and weight. The iodide salt is approximately 286.11 g/mol.
How is purity checked?
The current batch is independently HPLC tested above 99% and matched to an online batch report.
Is it intended for human use?
No. It is supplied only for controlled laboratory research.
Selected Scientific Sources
- Selective and membrane-permeable small-molecule inhibitors of NNMT.
- PubChem record for 5-amino-1-methylquinolinium iodide.
- Review of NNMT in obesity and metabolic research.
Research Resources
- NAD+ Research Compound
- SLU-PP-332 Research Compound
- Batch Verification and COAs
- Research Compound Storage Guide
- Browse All Research Peptides
For research use only. Not for human or veterinary use.
